Endocrine Abstracts

Bariatric surgery, in particular, Roux-en-Y gastric bypass (RYGB), is the most effective treatment for morbid obesity. The restricted gastric capacity and reduced absorption of nutrients cannot account for all the metabolic benefit we observe post-operation. Therefore, we applied metabolic and microbial profiling approach to investigate the potential mechanisms of RYGB surgery. Metabolic profiling strategy is widely applied in the discovery and development of metabolic biomark...

Introduction: Weight loss is a cornerstone in the management of prediabetes and diabetes mellitus. The association between weight and all-cause mortality is controversial and even paradoxical. Studies usually assess baseline weight. Studies assessing weight changes over time are limited. We present preliminary results of our attempt to model weight changes in patients with prediabetes and diabetes assessing the relationship with all-cause mortality.Metho...